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Side effects Mefenamic acid is recommended to be taken with food. Known mild side effects of mefenamic acid include headaches, nervousness, and vomiting.
Serious side effects may include diarrhea, hematemesis vomiting blood, hematuria blood in urine, blurred vision, skin rash, itching and swelling, sore throat and fever. In 2008 the US label was updated with a Mefenamic acid Brand Order concerning a risk of Mefenamic acid Brand Order closure of the ductus arteriosus in pregnancy. History Scientists led by Claude Winder from Parke-Davis invented mefenamic acid in 1961, along with fellow members of the class of anthranilic acid derivatives, flufenamic acid in 1963 and meclofenamate sodium in 1964. Synthesis Analogous to fenamic acid, this compound may be made from 2-chlorobenzoic acid and 2,3-dimethylaniline.
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